Animal reproduction research have not been performed Along with the drug combination-promethazine and codeine. It is far from acknowledged whether or not this drug combination may cause fetal harm when administered to the Expecting woman or can impact replica capacity.

Promethazine HCl Oral Option is contraindicated in comatose states, and in men and women recognized to get hypersensitive or to possess had an idiosyncratic reaction to promethazine or to other phenothiazines.

Promethazine needs to be made use of cautiously in individuals with cardiovascular disease or with impairment of liver operate.

Therapy adjunctive to meperidine or other analgesics for Charge of postoperative agony. Sedation in both of those youngsters and adults, and aid of apprehension and production of mild sleep from which the client is usually quickly aroused.

For preoperative medication kids involve doses of 0.five mg for each pound of entire body pounds in combination with the properly reduced dose of narcotic or barbiturate and the appropriate dose of an atropine-like drug.

Given that recurrences of NMS are already documented with phenothiazines, the reintroduction of promethazine HCl really should be cautiously considered.

g., those with evidence of greater intracranial pressure or brain tumors), Promethazine HCl and Codeine Phosphate Oral Solution could cut down respiratory drive, plus the resultant CO2 retention can further improve intracranial tension. Additionally, opioids produce adverse reactions which will obscure the medical program of people with head injuries.

Promethazine HCl and Codeine Phosphate Oral Alternative is indicated for the non permanent aid of coughs and upper respiratory indicators connected to allergy or the widespread chilly in patients 18 several years of age and older.

Promethazine HCl Oral Remedy needs to be made use of during pregnancy only if the potential advantage justifies the opportunity danger into the fetus.

Promethazine: Signs and signs of overdosage with promethazine HCl range between gentle despair in the central nervous method and cardiovascular program to profound hypotension,

Usually do not make use of a residence teaspoon to measure your medication. You might accidentally take excessive. You can request your pharmacist for the measuring machine you must use and the way to measure read more the correct dose.

When offered concomitantly with Promethazine HCl Oral Answer, the dose of barbiturates needs to be minimized by a minimum of one-50 percent, along with the dose of narcotics must be minimized by a single-quarter to 1-half. Dosage has to be individualized. Excessive amounts of promethazine HCl relative to your narcotic may well lead to restlessness and motor hyperactivity in the affected individual with agony; these signs usually disappear with ample control of the discomfort.

Human Knowledge Released details from circumstance-Manage and observational scientific tests on codeine use in the course of pregnancy are inconsistent inside their results. Some reports of codeine publicity showed an elevated risk of All round congenital malformations while others didn't.

Promethazine HCl Oral Resolution really should be applied cautiously in folks with heart problems or with impairment of liver perform.